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Congratulations to Dame for completing their clinical trial with Citruslabs

Natural Supplement for better mood and increased sexual desire


Dame worked with Citruslabs to research their "Vibe" gummy aimed at improving stress, anxiety, and libido in women aged 24-52. The study received IRB approval and was registered on This was an open-label single-arm clinical trial that used participant outcome methods for data collection. This means that there was one study group (the one that received the intervention); all participants received branded samples of the Dame products and had to complete baseline as well as intervention questionnaires. 

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About Dame

Supplements for getting women "out of their minds and into the moment"

Dame created their "Vibe" gummy in order to support women at every stage of their sexual experiences, by focusing on their mental and emotional well-being. As a pleasure-forward brand, Dame understands that female desire and arousal start with the mind and extends to the body. To create a holistic offering, Dame believes in going straight to the root cause of low libido and desire: stress. 

The brand believes in uplifting women and encouraging connectivity with yourself (or with a partner). They highlight the link between stress and sexual dysfunction and aim to fill this neglected area of research with their product.

Dame predicted that alleviating stress may boost sexual function, and developed a product to accomplish just that. Their other products have over 2,000 five-star reviews, and they were named one of 2020's Most innovative wellness companies by FastCompany. To ensure they keep delivering products that satisfy, Dame decided to test their new ideas by running a clinical study with Citruslabs. 

The product

Dame's Vibe Gummy contains a blend of 5 ingredients that target stress, anxiety and lowered sexual desire: SensorilⓇ ashwagandha, l-theanine, mucuna pruriens, rhodiola and shatavari. As heightened stress and anxiety have been linked to sexual dysfunction in women, this combination of plant-based ingredients was thoughtfully picked out to target these underlying issues.

Study design

The trial was a single-group, non-randomized, non-controlled, open-label observational trial that took place over four weeks. Participants took two of the Vibe gummies each day, while also completing surveys at baseline, 2 weeks, and 4 weeks. The surveys measured mood, anxiety, stress, sexual desire, and sexual satisfaction among other non-categorized well-being questions. The scores were converted into numerical measures and analyses were run to compare participants' outcomes. 

The participants

53 women aged 24-65 completed the study, 96% of which were in relationships during the study period. All participants had self-reported a decrease in sexual desire and experienced stressful or busy lifestyles.  


Quantifying the impact of Dame's Vibe Gummies

The observational study Dame conducted is a great first step and foundational for their research. It established a baseline for their products and their effects and performance. The next step for Dame would be to invest in a double-blind placebo-controlled study, the gold standard for clinical research. 

Aims & Objectives: To evaluate the effects of Dame's Vibe Gummies on anxiety, stress, mood, and sexual desire. 

Study design: Interventional and observational.

Methods: A total number of 55 participants with lowered sexual desire and stressful lifestyles were recruited to take a Dame jelly supplement for 4 weeks. The participants were surveyed using a questionnaire at baseline, 2 weeks, and 4 weeks, to assess symptoms of anxiety, stress, sexual dissatisfaction and overall wellbeing. 

Results: After using Vibe, 87% of participants experienced reduced anxiety and stress, 85% reported increased sexual desire and libido, and 75% reported increased satisfaction in their sexual life. 

Conclusion:  Dame's supplement showed promising results in women with self-reported sexual desire and satisfaction issues, as well as in improving mood and symptoms of stress and anxiety. Randomized control studies are suggested to further detail and quantify these results.


Dame's Vibe gummies lowered stress and increased sexual desire in majority of participants 

This single-group study of 53 women found the Dame product improved symptoms of anxiety and low mood, as well as increased sexual desire and satisfaction. 

At 4 Weeks 

87%  of study participants experienced less anxiety

85% of study participants' sexual desire increased

50% of study participants experienced improved mood AND increased desire

87%  of study participants reported less stress 

75% of study participants improved satisfaction in their sexual lives

74% of participants were most likely to recommend the test product to a friend

Stress, Anxiety and Mood

Stress and anxiety symptoms were significantly reduced in the majority of participants over the 4 week study. 


93% of participants reported significantly improved mood from baseline to each time point (P<0.001 between all timepoints). 87% of participants reported significant improvement of anxiety from baseline to each time point (P<0.001, baseline vs. 2 or 4 week). 87% of participants reported significant improvement (reduction) in stress from baseline to each time point (P<0.001, baseline vs. 2 or 4 week). 85% of participants reported significantly increased sexual desire and sexual satisfaction from baseline to each time point (P<0.001 between all timepoints).

Sexual Desire and Satisfaction

Participants largely experienced improved sexual desire and satisfaction, representing the largest change in ratings from baseline to 4 weeks. Additionally, over 50% of women reported improvements in this area alongside their improvements in mood, anxiety, and stress. 

Participants were also evaluated at week 4 on how satisfied they were with the Dame Vibe gummies and their likeliness to recommend the product to a friend. 74% of participants would recommend this product to a friend.


77% of participants reported a satisfaction score of 4 or 5 stars, revealing a very high satisfaction rate amongst users. 

About Citruslabs

Clinical trials for consumer brands 

Citruslabs’ mission is to provide robust, affordable clinical trials for brands. We are setting new standards for creating research-backed product claims for supplements, skincare products, devices, CBD products, health foods, and superfoods.

Citruslabs’ mission is to provide robust, affordable clinical trials for brands. We are setting new standards for creating research-backed product claims for supplements, skincare products, devices, CBD products, health foods and superfoods.

We can do it all

Study design

IRB process

Patient recruitment

Patient adherence 

Data collection

Data analysis

Product claims

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