Kintor Pharmaceutical, based in China has just finished enrolling patients for its phase II trial of a new treatment for Female Androgenetic alopecia (AGA).
The treatment, called pyrilutamide (KX-826), is an androgen receptor antagonist applied topically to treat both AGA and acne vulgaris.
The enrolment began around four months ago and resulted in a total of 160 patients. Going forward, the safety and efficacy will be measured through a randomized, double-blind, placebo-controlled clinical trial. The primary endpoint is variation in non-vellus target area hair counts (vellus hair is commonly called “peach fuzz” and is the fine hair that covers most of the body, so non-vellus hair counts look at the hair loss that occurs in other areas such as on the scalp and in the eyebrows.)
There are 15 hospitals taking part in the trial, all led by Pekin University People’s Hospital.
Last year, a similar trial on male participants using KX-826 met the primary endpoint with a favorable safety profile. Another phase II trial of male participants is taking place in the US, where the first patient has just been dosed, alongside the current female trial in China.
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