NEWS: Regeneron clinical trial hold Covid-19 patient enrollment in antibody trial

This week, Regeneron Pharmaceuticals have shown to put a hold on enrolling patients in the trial of REGN-COV2, where they are testing an antibody cocktail therapy for treating hospitalized patients who require high-flow oxygen or mechanical ventilation. REGN-COV2 is known to be a combination of two monoclonal antibodies named REGN10933 and REGN10987 and can block the infectivity of SARS-COV-2, the virus that causes Covid-19.


This decision follows the recommendations of an independent data monitoring committee (IDMC) based on a potential safety signal and an unfavorable risk/benefit profile at this time. Following the recommendation of the committee, Regeneron will continue to enroll hospitalized patients who are only requiring no oxygen or only low-flow oxygen. Regeneron underlined that the trial for hospitalized patients has been divided into four cohorts that are independently randomized. This means cohort 1 involved patients who require low-flow oxygen and cohort 1A will include patients who are not in need of oxygen.


The FDA (US Food and Drug Administration) is currently reviewing the antibody cocktail for potential emergency use authorization (EUA) in mild to moderate outpatients at high risk for poor outcomes.


The recommendation of the committee will also be a baseline for the decision of the independent committee, which is monitoring the RECOVERY trial evaluating REGN-COV2 in hospitalized patients in the United Kingdom.


Partner with accredited companies


Since 2015, our team has been hard at work raising awareness of clinical trials across the globe. A Forbes ‘30 Under 30’ company and a graduate of the renowned Techstar program in New York, Citruslabs is at the forefront of patient recruitment and retention technologies. With over 3 million patients now recorded on our databases, our patient recruitment dashboard is fast becoming the most efficient method of trial recruitment.

Now a #1 health app in 17 countries, our Mindmate app is helping to revolutionize the way we think about healthcare. Mindmate “[takes] senior care into the digital age” (Forbes, 2018) by providing people with the cognitive decline the essential tools to help them rebuild and maintain strong mental health. Trusted by millions of users, our health community continues to grow as the content available expands to the needs of individuals today.

With more than 200 research sites now using the Citrus platform to screen thousands of patients every month, researchers are now well on their way to finding new treatments for hundreds of different health conditions - something that just would not be possible without a technological solution. Make sure that your clinical trial is in the lucky 12% and turn that luck into guaranteed results with Citrus.

  • Interested in finding out more? Get in touch with us here, and check out our archives for all our top tips and tricks on running successful clinical trials in today's constantly changing industry.

Still a little unsure? Check out what our customers have to say about us here.


Citruslabs

Copyright © 2020

All rights reserved

MindMate Inc.

Company

Product

Support

  • LinkedIn
  • Twitter
  • Instagram

1639 11th Street, Suite B-208, Santa Monica, CA 90404