Retinol Clinical Trials




Retinol is one of the most popular ingredients in skincare, touted for its antiaging benefits. Retinol clinical trials have revealed significant effects of both natural and synthetic retinoids on markers of photo aging. Today, we’ll overview some of the clinical evidence for retinoids and look at our own retinol clinical trials.


Clinical Evidence

There are many clinical studies on various retinoid products, and the consensus seems to be that retinoids are effective ingredients in protecting the skin from photoaging. It is important to note the difference between intrinsic/chronological skin aging and photoaging. Intrinsic skin aging is inevitable and occurs over time as the skin naturally loses elasticity and cell turnover slows. This is not likely affected by retinol products, unlike photoaging (damage that occurs from cumulative UV exposure).


A recent literature review suggests retinoids are some of the most promising agents for preventing premature aging, namely when delivered through tretinoin. However, many forms of tretinoin are irritating to the skin, and dermatologists have shifted to recommending less harsh products such as adapalene.


Our retinol Clinical Research

We recently conducted a clinical trial with Common Heir, to assess their encapsulated retinol product. The Common Heir team prioritizes eco-friendly formulas that are kind to the earth and your skin, without sacrificing performance. You can read more about our study with them, here!


The results of their clinical trial with us revealed the retinol product’s effectiveness in improving participants’ skin, especially on measures of fine lines and wrinkles. We were able to publish the results of their study and create health claims from the statistical discoveries, which Common Heir can now use to market their retinol product.



We hope to conduct more retinol clinical trials in the future and create science-backed health claims brands can use to market their products effectively, as we have with Common Heir.


Want to create your own clinical trial?

Citruslabs provides a simple and affordable way to prove that your products actually work. At Citruslabs, we design a clinical trial that is right for you and your budget, so that you can start sharing research-backed product claims without spending a fortune. We offer the cohesive planning and management required to conduct successful clinical trials, from start to finish. Ready to get started? Let's talk! You can contact us here.