What to know about Retinol Clinical Trials




Retinol skincare has been hailed for its anti-aging properties, and recent research has attempted to compare the use of retinoic acid and all-trans-retinol in their treatment of wrinkles. Today, we’ll l overview some of the latest retinol clinical trials to summarize findings in this area.


Clinical Evidence for Retinol

Retinol and retinoic acid have both been shown to dramatically impact the skin’s appearance. Recent research found that four weeks of retinoid treatment resulted in increased epidermal thickness as well as upregulated counts of collage genes (type 1 and type 3).


Retinol clinical trials have included noninvasive imaging methods as well as skin biopsy. Research indicates topical applications of retinol cause significant changes in the cellular and molecular properties of the epidermis and dermis, resulting in minimized wrinkles and improved skin smoothness.


Retinol vs. Retinoic acid

Topical retinol treatments have been the primary retinoid skincare product for many years, but retinoic acid is proving to have similar results, and in be more effective in some areas. Retinoic acid was shown to induce changes in skin histology to a greater degree than retinol creams in a recent study.


The anti-aging effects of retinol and retinoic acid are highly similar, both will reduce the appearance of fine lines and wrinkles, as shown in several retinol clinical trials.


If you’re considering adding retinol to your routine, be sure to consult a dermatologist about what products are right for your skin type. Also note that retinol can increase the photosensitivity of the skin, and wearing daily sunscreen will become even more important.



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