Principal Investigator

A principal investigator is the lead researcher responsible for overseeing the study development, the research, and integrity of a clinical trial.

The principal investigator (PI) ensures the study follows all required regulatory guidelines, protects participant safety, and oversees proper study conduct. Most PIs lead a team of researchers and work closely with clinical staff, research teams, ethics committees and sponsors throughout the trial.

Want to better understand the PI’s role in clinical research? Read our blog post: "The Role of a Principal Investigator in Clinical Trials."