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The longevity market runs on hype. *Run on evidence.*

NAD+, NMN, resveratrol, spermidine — the ingredients are everywhere. The clinical evidence for your specific product? Almost nowhere. We fix that with biomarker-driven studies designed for the longevity buyer who reads the research.

How does Citruslabs run studies for Longevity? Citruslabs designs and runs IRB-approved clinical studies tailored to Longevity brands — consumer perception studies (4–8 weeks, $15K+), single-arm clinical studies (8–12 weeks, $40K+), or randomized controlled trials (12–16 weeks, $80K+). Each study uses category-appropriate endpoints and biomarkers, ships with a marketing claims appendix reviewed for FTC and FDA best practices, and earns the optional Citruslabs Tested Seal if the data supports product claims.

Clinical studies for longevity supplements with biomarker-driven endpoints and epigenetic testing.

Longevity buyers are the most *skeptical consumers alive*

Your customers listen to Huberman, follow Peter Attia, and read the actual papers. They know the difference between "contains NMN" and "clinically shown to increase NAD+ levels in a 12-week RCT." **Ingredient-level claims don't cut it in this market.** The longevity space is drowning in borrowed science and extrapolated mouse data. A clinical study on your actual formulation — with blood biomarkers, validated instruments, and real statistical significance — is the only way to earn credibility with this audience.

Contains NMN, which has been shown in preclinical studies to boost NAD+ levels

In a 12-week randomized controlled trial, participants taking [Product] showed a 42% increase in NAD+ levels and a 3.6-year reduction in biological age

Categories

NAD+ & NMN

NAD+ precursors like NMN and NR are the backbone of the longevity supplement market. We design biomarker-driven studies measuring blood NAD+ levels, epigenetic age, and cellular energy markers to substantiate your core claims.

Anti-Aging & Senolytics

Senolytic compounds like fisetin and quercetin target aging at the cellular level. We measure inflammatory markers, senescence biomarkers, and biological age to validate your anti-aging formulation.

Cognitive & Nootropics

Brain health is a top longevity priority. We pair validated cognitive battery testing with wearable sleep data and blood biomarkers to substantiate nootropic and neuroprotective claims.

Mitochondrial & Energy

CoQ10, PQQ, and mitochondrial support compounds need objective energy and performance data. We measure exercise capacity, metabolic markers, and subjective energy alongside wearable activity data.

Adaptogens & Stress

Ashwagandha, rhodiola, and adaptogenic formulas need cortisol data and HRV trends to back their claims. We measure salivary cortisol patterns, wearable HRV, and validated stress instruments.

Gut & Microbiome

The gut-longevity axis is a growing category. We coordinate at-home stool kits, measure microbial diversity and barrier function markers, and pair them with inflammatory blood panels.

Study Types

Frequently Asked Questions

What biomarkers do you measure?
We offer a comprehensive panel including blood-based biomarkers (NAD+, inflammatory markers, lipid panels, metabolic health), epigenetic age testing (Horvath, GrimAge, PhenoAge clocks), wearable data (HRV, sleep, activity via Oura/Whoop/Apple Watch), CGM integration (glucose variability, time in range), and validated cognitive assessments. We customize the panel to your specific claims goals.
How is a longevity study different from a standard supplement study?
Longevity studies require harder endpoints — blood panels, epigenetic testing, and wearable data rather than just perception surveys. The longevity consumer expects biomarker data, statistical significance, and study designs rigorous enough for peer-reviewed publication. We design every study with this audience in mind.
Can my study be published in a peer-reviewed journal?
Yes. We design studies with publication-grade methodology — pre-registered endpoints, proper randomization, ITT analysis, and biomarker validation. Many of our longevity brand partners have published their results, which opens doors to practitioner channels and medical credibility.
How long does a longevity study take?
Most longevity RCTs run 8-16 weeks for the intervention period, with 4-6 weeks of setup and recruitment beforehand. Biomarker collection (blood draws, epigenetic testing) happens at baseline and endpoint. We provide interim data check-ins and a final marketing-ready report with claims, data visualizations, and statistical analysis.
What's the minimum sample size?
For biomarker-driven longevity studies, we typically recommend 40-80 participants per arm for adequate statistical power. The exact number depends on your primary endpoint, expected effect size, and whether you're running a two-arm (treatment vs. placebo) or multi-arm design. We help you power the study correctly during the design phase.
Do participants need to come to a lab for blood draws?
Not necessarily. We offer both in-clinic phlebotomy and at-home blood draw services via mobile phlebotomy networks. Wearable data and cognitive assessments are fully remote. Epigenetic testing uses at-home saliva kits. We design the logistics around participant convenience to maximize retention.

Testimonials

Our target customer reads PubMed before they buy supplements. The Citruslabs study gave us a white paper we could link from our PDP. Our conversion rate went up 34% in the first quarter.

Daniel Torres, CEO & Co-Founder at NAD+ Brand

We included blood panels, epigenetic testing, and Oura Ring data. The level of biomarker integration Citruslabs offered was something we couldn't find at any other CRO at this price point.

Dr. Sarah Lin, VP Clinical at Longevity Startup

The study was designed to be publishable from day one. We submitted to a peer-reviewed journal within weeks of receiving our final report. That publication changed how practitioners view our brand.

Marcus Webb, Head of R&D at Adaptogen Company